Differential Involvement of the P2Y1and P2Y12Receptors in Platelet Procoagulant Activity
نویسندگان
چکیده
منابع مشابه
Differential involvement of the P2Y1 and P2Y12 receptors in platelet procoagulant activity.
OBJECTIVE In vivo, activated platelets contribute to the initiation of thrombin generation through the exposure of phosphatidylserine to form a procoagulant catalytic surface and through platelet-leukocyte interactions, which lead to the exposure of leukocyte tissue factor (TF). On the basis of observations that the platelet P2Y1 and P2Y12 receptors both contribute to thrombosis and thrombin fo...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2003
ISSN: 1079-5642,1524-4636
DOI: 10.1161/01.atv.0000092127.16125.e6